https://sowonjae.dongjedang.com/en/tags/%ED%86%B5%EC%A6%9D%EC%B9%98%EB%A3%8C/ Recent content in 통증치료 on Sowonjae — Studies in Sasang Constitutional Medicine Hugo en Wed, 10 Jun 2026 00:30:00 +0900 https://sowonjae.dongjedang.com/en/post/2026-06-10-fascia-mechanobiology-dose-response/ Wed, 10 Jun 2026 00:30:00 +0900 https://sowonjae.dongjedang.com/en/post/2026-06-10-fascia-mechanobiology-dose-response/ <!-- 자동 생성. 원천은 <slug>.md 의 translation_en. 직접 수정하지 말 것. --> <h2 id="1-abstract">1. Abstract</h2> <p>When chronic pain returns after treatment, the failure is usually attributed to the treatment itself. Connective-tissue mechanobiology points elsewhere. The pain returns because the mechanical and biochemical environment that produced it has not changed. Fibroblasts respond to mechanical load along a curve rather than a straight line. Excessive load drives inflammation, fibrosis, and neural sensitization. Insufficient load leaves the tissue sclerotic, atrophic, and cross-linked. Only an intermediate range rebuilds and strengthens collagen. The aim of treatment, then, is not to remove the stimulus but to move trapped tissue back into that intermediate range. Korean medicine addresses this curve from two sides. External treatment (外治, <em>oechi</em>—therapies applied from outside the body) acts locally along three axes: a mechanical axis that works the tissue directly (acupuncture, the blade-needle <em>dochim</em>, thread-embedding), a thermal axis that delivers heat to the deep layers (heated fire-needling), and a pharmacological axis that governs inflammation, lavage, and regeneration (bee-venom and herbal pharmacopuncture). On the mechanical axis, two variables must be kept distinct: the intensity of the stimulus (rotation, depth, gauge) and the mode of action of the tip (pressing versus cutting). This distinction separates the ordinary filiform needle from the <em>dochim</em>. External treatment handles local input; internal treatment (內治, <em>naechi</em>—therapies taken into the body), comprising herbal medicine and constitutional detoxification, addresses the systemic biochemical milieu beneath it. The six-stage roadmap arranges these along the dose-response curve. Direct evidence for the later stages and for thread-embedding is limited, and they are presented here as a hypothetical model.</p>